L-5-MTHF provides a natural, biologically active form of folate. Folate is essential for cell division and growth, and also works to balance the homocysteine pathway. This formula provides a generous 5 mg per capsule of folate in the bioidentical, bioactive form, 5-methyltetrahydrofolate. L-5-MTHF (the L signifying that it is the all-natural [6S] isomer) is the active circulating form of folate found in the body and one of the several forms found in food. In nature it is found only as this [6S] isomer, which is why DFH uses L-5-MTHF, the natural isomer, rather than the mixed (or racemic) form.Our L-5-MTHF uses the patented folate derivative Quatrefolic. This innovative form of folate has demonstrated high bioavailability and solubility as well as long lasting stability. Quatrefolic® L-5-MTHF helps to increase blood folate levels much better than folic acid.