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Buffered Vitamin C w/ Bioflavanoids 90 caps by Metabolic Maintenance

A powerful antioxidant, vitamin C is a water-soluble vitamin necessary to form collagen in bones, cartilage, muscle and blood vessels. It also aids in the absorption of iron. We use only USP-quality (99.5% or higher purity) vitamin C, with a pH equal to 2.4. For patients who want to supplement their diet with additional vitamin C, our buffered formulas combine low-acidity potassium/ magnesium ascorbate with lemon bioflavonoids including hesperidin and rutin. 

  • Nourishes tissue growth and repair
  • Supports adrenal and immune function*
  • Powerful antioxidant
  • Gentler on sensitive stomachs

Each size 000 vegetarian cellulose capsule contains:


Vitamin C (as Potassium Magnesium Ascorbate )

1000 mg

Magnesium (as Potassium Magnesium Ascorbate)

38 mg

Potassium (as Potassium Magnesium Ascorbate)

94 mg

Lemon Bioflavonoids (includes 80 mg of Rutin and 80 mg of Hesperidin)

200 mg

  Other ingredient: vegetarian cellulose capsule



A powerful antioxidant, vitamin C is a water-soluble vitamin necessary to form collagen in bones, cartilage, muscle, and blood vessels. It also aids in the absorption of iron. If you are looking for a vitamin C supplement, but have a sensitivity to acids, our buffered formula is an excellent choice. Low-acidity potassium/magnesium ascorbate delivers either a 500mg or 1000 mg dose of vitamin C along with essential minerals potassium and magnesium, as well as lemon bioflavonoids (including hesperidin and rutin), as ascorbates are more readily absorbed in combination with flavonoids than they are when taken alone. 


Product Description: 

What is Buffered Vitamin C with Bioflavonoids?

Designed specifically for individuals sensitive to acidic foods and beverages, Buffered Vitamin C 500mg and 1000 mg with Bioflavonoids is a combination of two mineral ascorbates (potassium and magnesium) that supply the essential antioxidant vitamin C without increasing stomach acidity.  

Vitamin C is a potent water-soluble antioxidant and essential in the human diet as it cannot be synthesized within the body [1]. Vitamin C is an electron donor, and this property is closely related to all of its known functions [1]. Vitamin C is required for the production and maintenance of collagen. It has anti-inflammatory properties, supports the immune system, contributes to the healthy production of neurotransmitters, and aids in the absorption of iron.

Lemon bioflavonoids have been added for increased bioavailability.


How does Buffered Vitamin C with Bioflavonoids Work?

The stability and formation of collagen, the major protein from which connective tissue, cartilage, bone, skin, tendon, and tooth dentin is made, requires a vitamin C-mediated process [2]. A lack of vitamin C, a required cofactor for prolyl hydroxylase, impairs the development of collagen and renders humans “scorbutic” [2]. The human phenotype of vitamin C deficiency, “scurvy” classically involves fragility of blood vessels [2].

In addition to its antiscorbutic actions, vitamin C has potent antioxidant properties. Antioxidants protect and aid in the repair of cellular damage caused by free radicals/reactive oxygen species. In response to physical trauma, vitamin C exerts a protective effect on neutrophil-mediated cell injury by scavenging reactive oxygen metabolites [3]. Vitamin C concentrations in plasma and immune cells rapidly decline during infections and stress signifying its use is upregulated for immune support [4]. Multiple clinical studies have shown that supplementation of vitamin C improves components of the human immune system [4]. Vitamin C also plays a role in the maintenance of healthy circulation and has anti-inflammatory effects [2]. 

Of all the body’s organs, the adrenal glands accumulate the highest levels of vitamin C [5]. Animal models have shown the role of vitamin C in these tissues is crucial to survival [5]. Ascorbic acid is a cofactor required for the biosynthesis of and the catecholamine neurotransmitters, epinephrine, norepinephrine, and dopamine, as well as adrenal steroidogenesis [5]. 

For those consuming plant-based diets (no animal tissue), vitamin C is the only known dietary constituent that can significantly increase the absorption of nonheme iron [6]. It is important to note, the stimulating influence of ascorbic acid on iron absorption has been demonstrated to be most pronounced when ascorbic acid is consumed with food [6].

Flavonoids, and specifically hesperidin and rutin, work synergistically with vitamin C, as ascorbates are more readily absorbed in combination with flavonoids than they are when taken alone [7]. Flavonoids also have antioxidant and anti-inflammatory properties of their own.


What are the Suggested Uses for Buffered Vitamin C with Bioflavonoids?

  • Nourishes tissue growth and repair as a collagen support nutrient.
  • Supports adrenal and immune function, bolstering immune cells and contributing to the production of catecholamines.
  • Powerful antioxidant for free radical protection and repair.
  • Can increase absorption of iron from food.
  • Gentler on sensitive stomachs than classic ascorbic acid vitamin C supplements


Source Materials: Potassium magnesium ascorbate is made by combining ascorbic acid (corn sorbitol fermentation) with magnesium oxide and potassium chloride (mined or extracted from salt water). Lemon Bioflavonoids are 100% lemon. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.


Allergens: According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.


Recommendations: One (1) capsule daily with a meal, or as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.



  1. Padayatty, Sebastian J., et al. "Vitamin C as an antioxidant: evaluation of its role in disease prevention." Journal of the American college of Nutrition 22.1 (2003): 18-35.
  2. Libby, Peter, and Masanori Aikawa. "Vitamin C, collagen, and cracks in the plaque." (2002): 1396-1398.
  3. Nieman, David C., et al. "Influence of vitamin C supplementation on oxidative and immune changes after an ultramarathon." Journal of applied physiology 92.5 (2002): 1970-1977.
  4. Wintergerst, Eva S., Silvia Maggini, and Dietrich H. Hornig. "Immune-enhancing role of vitamin C and zinc and effect on clinical conditions." Annals of Nutrition and Metabolism 50.2 (2006): 85-94.
  5. Patak, P., H. S. Willenberg, and S. R. Bornstein. "Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla." Endocrine research 30.4 (2004): 871-875.
  6. Cook, James D., and Manju B. Reddy. "Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet." The American journal of clinical nutrition 73.1 (2001): 93-98.
  7. Vinson, Joe A., and Pratima Bose. "Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract." The American journal of clinical nutrition 48.3 (1988): 601-604.


* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.