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L-Methylfolate 10 Milligrams 90 caps Metabolic Maintenance

​Folic acid, the most common form of folate in supplements and fortified foods, requires the enzyme methylenetetrahydrofolate reductase (MTHFR) to be converted to L-methylfolate, the activated form of folate used by the body for many biochemical reactions. About half of the population have genetic variations that reduce the ability of the MTHFR enzyme to make this conversion. For this population, L-methylfolate supplementation is far more effective in providing this form of folate.

  • Supports healthy mood, cardiovascular, and nerve function*
  • Important for normal production of serotonin, norepinephrine and dopamine*
  • Essential for converting homocysteine to methionine*


L-Methylfolate 10 mg


Product Code: 00519              Capsules per Bottle: 90


Each size 3 vegetarian cellulose capsule contains:


Folate (10 mg folate from 13.7 mg L-5-Methylfolate, calcium salt)

16.7 mg DFE


260 mg



L-methylfolate is the activated form of folate (vitamin B-9) ready to be used by the body for many biochemical reactions. Unlike folic acid, the synthetic form of folate found in most supplements and fortified foods, L-methylfolate does not require conversion by the MTHFR enzyme, a function that is impaired by genetic variations present in about half the population. The supplement is not exclusively for those with an MTHFR mutation however, those without the inhibitory genetic defect can absorb and use L-methylfolate as well.


What is L-Methylfolate?

Low folate status is one of the most common nutritional deficiencies, and that statistic inc