Indications: For temporary relief of sleep disorders, joint pain, mood swings, depression, obsessive/compulsive behavior, joint pain, lethargy, Seasonal Affective Disorder, itching, sleep disorders, and poor appetite. Description: Serotonin is a neurotransmitter of major importance in brain chemistry. It is responsible for regulation of appetite, sleep control and when deficiencies occur, some emotional tendencies such as aggression and obsessive-compulsive disorders. Serotonin is metabolized from the essential amino acid tryptophan, which can be derived from indole through pancreatic degradation in the small intestine. Additionally, its presence is noted in a wide array of food sources such as pineapple, banana, kiwi fruit, plum, tomato, walnuts and others.Serotonin is a neurotransmitter produced in the brain known to influence the functioning of the brain, cardiovascular, renal, immune, and gastrointestinal systems. It is known to modulate mood, emotion, sleep and appetite and thus is implicated in the control of numerous behavioral and physiological functions. Any disruption in the synthesis, metabolism or uptake of this neurotransmitter has been found to be partly responsible for certain manifestations of schizophrenia, depression, compulsive disorders and learning problems.Serotonin originates in neurons deep in the midline of the brainstem. Because these neurons profile diffusely throughout the brain, serotonin can affect various brain functions. It also interacts with many other neurotransmitters, either directly through neurons that use both serotonin and another neurotransmitters, or by serotonin neurons influencing neurons that primarily use these other transmitters. The diffuse connections of serotonin allow it to affect many basic psychological functions such as anxiety mechanisms and the regulation of mood, thoughts, aggression, appetite, sex drive and the sleep/wake cycle. Multiple observations suggest that serotonin, one of the most abundant neurotransmitters, plays an important role in the regulation of mood and a key role in the treatment of depression.